Reduces the exudation, helps reduce capillary permeability, reduces the migration of leukocytes and lymphocytes in the area of inflammation, does catabolic action inhibits the growth of connective tissue and deposition of collagen, reduces scarring. Method of production of drugs: Table., Film-coated, 50 mg, 150 mg. Side effects and complications in the use of drugs: drowsiness, weakness, dizziness, dry mouth, sleep disorders, hallucinations, muscle weakness, here gastrointestinal disorders, increased activity As directed hepatic transaminases, hepatitis G, reducing blood pressure, bradycardia, fatigue, AR (skin itching, rash, urticaria). Pharmacotherapeutic group: M03BX02 - centrally acting muscle relaxants. The main pharmaco-therapeutic effects: muscle relaxants central action, the exact mechanism of action is unknown, as a result of anesthesia membranostabilizing and prevents the stimulation in primary afferent fibers, mono-blocking and spinal cord reflexes polisynaptychni; secondary mechanism of action is blocking the release ancients transmitter by the blockade of calcium ion in revenue synapses, reduces reflex readiness retykulospinalnyh ways the brain stem, enhances peripheral circulation. Method of production of drugs: Cream 1% to 5 g, 0,1% 15 g ancients for external use only 1% to 10 g to 15 g emulsion Cutaneous 0,1% to 30 G Pharmacotherapeutic group D07AS01 - corticosteroids for use in dermatology ancients . Dosing and Administration of drugs: dosage set individually for adults at the beginning of treatment, in severe diseases g daily dose is typically 50-75 mg of Mts diseases and in less severe cases prescribed in the ancients dose of 20-30 mg / day maintenance dose is 5-15 mg / day, children the initial dose for the treatment of diseases G 1-2 mg / kg body weight, daily maintenance dose of long-term treatment of 0,25-0,5 mg / kg of body weight daily dose recommended to take one or double the daily dose - in a day, taking into account the circadian rhythm of endogenous GC secretion, in the range 6.8 h morning, a large daily dose can be split 2-4 ways, with the morning should take most of the daily dose, treatment should not Fluorescent Treponemal Antibody abruptly GC pause, to reduce the dose gradually, with the / V and V / m input dose, duration of ancients and multiplicity are determined individually: usually drug is administered in a dose of 30-45 mg / ancients slowly, if at / in writing is impossible, you can type in / m deep, and after removal of g if necessary, treatment can continue internally in the table. Contraindications to the use of drugs: hypersensitivity to the drug, severe myasthenia, lactation, relative contraindications - pregnancy, especially the first trimester. Method ancients production of drugs: Table. Pharmacotherapeutic group: D07AB02 - corticosteroids for use ancients dermatology. The main pharmaco-therapeutic action: the skeletal muscles relaxant central action, stimulating the presynaptic alpha2A-blockers receptors, it inhibits the release of exciting amino acids that stimulate the receptors of N-methyl-D-aspartat (NMDA-receptors), resulting in intermediate levels of spinal neurons is inhibition synaptic transmission of excitation, as this mechanism is responsible for excessive muscle tone, its oppression of muscle ancients decreases, in addition to miorelaksuyuchyh properties of the drug also shows central ancients anal'gezyruyuschee effect, No change as of G painful muscle spasms, and in HR. Contraindications to the use of drugs: dermatitis, complicated by a bacterial (eg, pyoderma, tuberculosis and syphilis), viral (eg orofatsialnyy herpes, chicken pox, shingles, genital warts, warts, contagious mollusk), fungal and parasitic (eg itching) infections ; ulcerative skin diseases, wounds, dermatitis around the mouth, atrophic Multiple Endocrine Neoplasia lesions, rosacea on the face, acne, ichthyosis, juvenile plantar dermatosis, angiasthenia skin hypersensitivity to the drug or corticosteroids, children age 6 months. Pharmacotherapeutic group: M03BX04 - centrally acting muscle relaxants.
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